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Drug interactions

Erythromycin + Temocillin

Severity: Minor

Erythromycin and Temocillin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

A bacteriostatic macrolide may theoretically diminish the killing activity of temocillin. No well-documented clinical failures are known.

What this interaction means in plain words

Erythromycin and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical pharmacodynamic antagonism between a bacteriostatic macrolide and a bactericidal cell wall inhibitor.

What to do

No routine change is needed; monitor clinical response and avoid unnecessary co-prescription.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Erythromycin with Temocillin?

MediHelp rates the interaction as minor. Erythromycin and Temocillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. A bacteriostatic macrolide may theoretically diminish the killing activity of temocillin. No well-documented clinical failures are known.

How serious is the interaction between Erythromycin and Temocillin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor clinical response and avoid unnecessary co-prescription.

What other medicines interact with Erythromycin?

MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.

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