Drug interactions
Erythromycin + Valoctocogene roxaparvovec
Severity: Moderate
Erythromycin and Valoctocogene roxaparvovec: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valoctocogene roxaparvovec commonly raises liver enzymes, and other hepatotoxic drugs may add to this risk. Erythromycin has occasionally been linked to liver injury.
What this interaction means in plain words
Erythromycin and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Erythromycin belongs to Anti Bacterial; Valoctocogene roxaparvovec belongs to Miscellaneous.
Why it happens
Additive hepatotoxic potential.
What to do
Monitor ALT and other liver tests regularly after gene therapy and consider a non-hepatotoxic antibiotic if enzymes rise.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Other interactions of Valoctocogene roxaparvovec
Frequently asked questions
Can I take Erythromycin with Valoctocogene roxaparvovec?
MediHelp rates the interaction as moderate. Erythromycin and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Valoctocogene roxaparvovec commonly raises liver enzymes, and other hepatotoxic drugs may add to this risk. Erythromycin has occasionally been linked to liver injury.
How serious is the interaction between Erythromycin and Valoctocogene roxaparvovec?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests regularly after gene therapy and consider a non-hepatotoxic antibiotic if enzymes rise.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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