Drug interactions
Erythromycin stearate + Oxcarbazepine
Severity: Moderate
Erythromycin stearate and Oxcarbazepine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxcarbazepine may modestly lower erythromycin concentrations via CYP3A4 induction. This could reduce antibacterial effectiveness. The effect is generally modest and manageable.
What this interaction means in plain words
Erythromycin stearate and Oxcarbazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Oxcarbazepine induces CYP3A4, increasing erythromycin metabolism.
What to do
Monitor clinical response to the antibiotic and consider an alternative agent if infection responds poorly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxcarbazepine
- Cabotegravir + Oxcarbazepine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Oxcarbazepine Major
- Atazanavir + Oxcarbazepine Major
- Benzhydrocodone / acetaminophen + Oxcarbazepine Major
- Bictegravir + Oxcarbazepine Major
Frequently asked questions
Can I take Erythromycin stearate with Oxcarbazepine?
MediHelp rates the interaction as moderate. Erythromycin stearate and Oxcarbazepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxcarbazepine may modestly lower erythromycin concentrations via CYP3A4 induction. This could reduce antibacterial effectiveness. The effect is generally modest and manageable.
How serious is the interaction between Erythromycin stearate and Oxcarbazepine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to the antibiotic and consider an alternative agent if infection responds poorly.
What other medicines interact with Oxcarbazepine?
MediHelp also lists interactions of Oxcarbazepine with, for example, Cabotegravir, Rilpivirine, Artemether / lumefantrine. The full list is on the Oxcarbazepine page.
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