Drug interactions
Erythromycin stearate + Triptorelin
Severity: Moderate
Erythromycin stearate and Triptorelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Erythromycin is a recognized cause of QT prolongation and torsades de pointes, and triptorelin may add modest QT lengthening. The combination may increase arrhythmia risk, particularly in patients with cardiac disease or electrolyte disturbance.
What this interaction means in plain words
Erythromycin stearate and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation; erythromycin blocks hERG potassium channels.
What to do
Consider an alternative antibiotic with less QT effect in at-risk patients. If used, check ECG and correct potassium and magnesium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triptorelin
Frequently asked questions
Can I take Erythromycin stearate with Triptorelin?
MediHelp rates the interaction as moderate. Erythromycin stearate and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Erythromycin is a recognized cause of QT prolongation and torsades de pointes, and triptorelin may add modest QT lengthening. The combination may increase arrhythmia risk, particularly in patients with cardiac disease or electrolyte disturbance.
How serious is the interaction between Erythromycin stearate and Triptorelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider an alternative antibiotic with less QT effect in at-risk patients. If used, check ECG and correct potassium and magnesium.
What other medicines interact with Triptorelin?
MediHelp also lists interactions of Triptorelin with, for example, Amisulpride, Arsenic trioxide, Bedaquiline. The full list is on the Triptorelin page.
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