Drug interactions
Escitalopram + Timolol
Severity: Minor
Escitalopram and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Escitalopram is a weak CYP2D6 inhibitor and might slightly raise timolol exposure, since timolol is partly metabolized by CYP2D6. The effect is expected to be small, though enhanced beta-blockade such as bradycardia is conceivable.
What this interaction means in plain words
Escitalopram and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Escitalopram belongs to Central Nervous System; Timolol belongs to Cardiovascular.
Why it happens
Weak inhibition of CYP2D6-mediated timolol metabolism by escitalopram.
What to do
No routine action is needed. Check heart rate if bradycardia or dizziness develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Other interactions of Escitalopram
- Cisapride + Escitalopram Contraindicated
- Citalopram + Escitalopram Contraindicated
- Escitalopram + Isocarboxazid Contraindicated
- Escitalopram + Methylene blue Contraindicated
- Escitalopram + Phenelzine Contraindicated
- Escitalopram + Pimozide Contraindicated
Frequently asked questions
Can I take Escitalopram with Timolol?
MediHelp rates the interaction as minor. Escitalopram and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Escitalopram is a weak CYP2D6 inhibitor and might slightly raise timolol exposure, since timolol is partly metabolized by CYP2D6. The effect is expected to be small, though enhanced beta-blockade such as bradycardia is conceivable.
How serious is the interaction between Escitalopram and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Check heart rate if bradycardia or dizziness develops.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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