Drug interactions
Ether + Propranolol
Severity: Moderate
Ether and Propranolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both beta blockers and ether anesthesia depress myocardial contractility, so the combination can cause hypotension and reduced cardiac output. Impaired compensatory tachycardia increases the risk during anesthesia.
What this interaction means in plain words
Ether and Propranolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive negative inotropic effects from beta blockade and anesthetic myocardial depression.
What to do
Inform the anesthesiologist about propranolol use and monitor hemodynamics continuously. Do not abruptly stop chronic beta blockers perioperatively unless directed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
- Arformoterol + Propranolol Major
Frequently asked questions
Can I take Ether with Propranolol?
MediHelp rates the interaction as moderate. Ether and Propranolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both beta blockers and ether anesthesia depress myocardial contractility, so the combination can cause hypotension and reduced cardiac output. Impaired compensatory tachycardia increases the risk during anesthesia.
How serious is the interaction between Ether and Propranolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Inform the anesthesiologist about propranolol use and monitor hemodynamics continuously. Do not abruptly stop chronic beta blockers perioperatively unless directed.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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