Drug interactions
Ether + Timolol
Severity: Moderate
Ether and Timolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both beta-blockers and volatile anesthetics such as ether depress myocardial contractility and conduction. Combined use can produce hypotension, bradycardia and reduced cardiac output during anesthesia.
What this interaction means in plain words
Ether and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive negative inotropic and chronotropic effects through pharmacodynamic synergism.
What to do
Inform the anesthesiologist of timolol use and monitor hemodynamics and ECG during anesthesia. Have anticholinergics and vasopressors available to treat bradycardia and hypotension.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
- Atenolol-chlorthalidone + Timolol Major
Frequently asked questions
Can I take Ether with Timolol?
MediHelp rates the interaction as moderate. Ether and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both beta-blockers and volatile anesthetics such as ether depress myocardial contractility and conduction. Combined use can produce hypotension, bradycardia and reduced cardiac output during anesthesia.
How serious is the interaction between Ether and Timolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Inform the anesthesiologist of timolol use and monitor hemodynamics and ECG during anesthesia. Have anticholinergics and vasopressors available to treat bradycardia and hypotension.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Timolol page.
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