Drug interactions
Etidronate + Foscarnet
Severity: Moderate
Etidronate and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can lower serum calcium: etidronate by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may increase the risk of symptomatic hypocalcemia.
What this interaction means in plain words
Etidronate and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Etidronate belongs to Musculoskeletal; Foscarnet belongs to Anti Virals.
Why it happens
Additive lowering of serum calcium through bone resorption inhibition and chelation of ionized calcium.
What to do
Monitor calcium, magnesium and ionized calcium during foscarnet therapy and replace deficits promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Etidronate
- Aluminum hydroxide + Etidronate Moderate
- Calcium acetate + Etidronate Moderate
- Calcium carbonate + Etidronate Moderate
- Calcium chloride + Etidronate Moderate
- Calcium citrate + Etidronate Moderate
- Calcium gluconate + Etidronate Moderate
Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Etidronate with Foscarnet?
MediHelp rates the interaction as moderate. Etidronate and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower serum calcium: etidronate by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may increase the risk of symptomatic hypocalcemia.
How serious is the interaction between Etidronate and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor calcium, magnesium and ionized calcium during foscarnet therapy and replace deficits promptly.
What other medicines interact with Etidronate?
MediHelp also lists interactions of Etidronate with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Etidronate page.
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