Drug interactions
Exenatide injectable + Levonorgestrel
Severity: Minor
Exenatide injectable and Levonorgestrel: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Exenatide slows gastric emptying and may delay or reduce the absorption of oral drugs, including oral contraceptives. Progestins may also slightly impair glucose tolerance, and the net effect is typically small.
What this interaction means in plain words
Exenatide injectable and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Delayed gastric emptying by exenatide may alter absorption of oral levonorgestrel, with minor pharmacodynamic opposition to glucose control.
What to do
Take oral levonorgestrel at least one hour before exenatide injection, and monitor blood glucose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levonorgestrel
Frequently asked questions
Can I take Exenatide injectable with Levonorgestrel?
MediHelp rates the interaction as minor. Exenatide injectable and Levonorgestrel have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Exenatide slows gastric emptying and may delay or reduce the absorption of oral drugs, including oral contraceptives. Progestins may also slightly impair glucose tolerance, and the net effect is typically small.
How serious is the interaction between Exenatide injectable and Levonorgestrel?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oral levonorgestrel at least one hour before exenatide injection, and monitor blood glucose.
What other medicines interact with Levonorgestrel?
MediHelp also lists interactions of Levonorgestrel with, for example, Amobarbital, Apalutamide, Belzutifan. The full list is on the Levonorgestrel page.
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