Drug interactions
Fenbufen + Timolol
Severity: Minor
Fenbufen and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs such as fenbufen can blunt the antihypertensive effect of beta-blockers through prostaglandin inhibition and sodium and fluid retention. Both can modestly raise potassium, although this is rarely significant with normal renal function.
What this interaction means in plain words
Fenbufen and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
NSAID inhibition of renal prostaglandin synthesis, causing fluid retention that opposes beta-blocker antihypertensive action.
What to do
Monitor blood pressure if fenbufen is used for more than a few days, and check potassium in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Fenbufen and Timolol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Frequently asked questions
Can I take Fenbufen with Timolol?
MediHelp rates the interaction as minor. Fenbufen and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. NSAIDs such as fenbufen can blunt the antihypertensive effect of beta-blockers through prostaglandin inhibition and sodium and fluid retention. Both can modestly raise potassium, although this is rarely significant with normal renal function.
How serious is the interaction between Fenbufen and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if fenbufen is used for more than a few days, and check potassium in patients with renal impairment.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
