Drug interactions
Fenofibrate micronized + Insulin glargine-lixisenatide
Severity: Minor
Fenofibrate micronized and Insulin glargine-lixisenatide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fibrates may improve insulin sensitivity and have been associated with enhanced glucose lowering in patients taking insulin. Hypoglycemia is possible, especially if the patient is poorly nourished or has low albumin.
What this interaction means in plain words
Fenofibrate micronized and Insulin glargine-lixisenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Probable additive improvement in insulin sensitivity; the mechanism is not firmly established.
What to do
Check blood glucose after starting or stopping fenofibrate and lower the insulin dose if glucose falls.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin glargine-lixisenatide
- Albiglutide + Insulin glargine-lixisenatide Major
- Chlorpropamide + Insulin glargine-lixisenatide Major
- Dulaglutide + Insulin glargine-lixisenatide Major
- Ethanol + Insulin glargine-lixisenatide Major
- Exenatide injectable + Insulin glargine-lixisenatide Major
- Glimepiride + Insulin glargine-lixisenatide Major
Frequently asked questions
Can I take Fenofibrate micronized with Insulin glargine-lixisenatide?
MediHelp rates the interaction as minor. Fenofibrate micronized and Insulin glargine-lixisenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fibrates may improve insulin sensitivity and have been associated with enhanced glucose lowering in patients taking insulin. Hypoglycemia is possible, especially if the patient is poorly nourished or has low albumin.
How serious is the interaction between Fenofibrate micronized and Insulin glargine-lixisenatide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose after starting or stopping fenofibrate and lower the insulin dose if glucose falls.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
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