Drug interactions
Fenoprofen + Garlic
Severity: Minor
Fenoprofen and Garlic: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements may have mild antiplatelet activity, which could add to the bleeding risk of an NSAID. Clinical evidence is limited to case reports and small studies.
What this interaction means in plain words
Fenoprofen and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fenoprofen belongs to Musculoskeletal; Garlic belongs to Gastrointestinal Tract.
Why it happens
Possible additive platelet inhibition from garlic constituents and NSAID COX inhibition.
What to do
Counsel patients on high-dose garlic supplements to report unusual bruising or bleeding; no routine change is needed for dietary amounts.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Fenoprofen with Garlic?
MediHelp rates the interaction as minor. Fenoprofen and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements may have mild antiplatelet activity, which could add to the bleeding risk of an NSAID. Clinical evidence is limited to case reports and small studies.
How serious is the interaction between Fenoprofen and Garlic?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients on high-dose garlic supplements to report unusual bruising or bleeding; no routine change is needed for dietary amounts.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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