Drug interactions
Fenoprofen + Valganciclovir
Severity: Minor
Fenoprofen and Valganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenoprofen may slightly raise exposure to ganciclovir, the active metabolite of valganciclovir, by competing for renal secretion. This is mostly relevant with renal impairment because ganciclovir can cause myelosuppression.
What this interaction means in plain words
Fenoprofen and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fenoprofen belongs to Musculoskeletal; Valganciclovir belongs to Anti Virals.
Why it happens
Competition for renal tubular secretion via organic anion transporters.
What to do
No routine adjustment is needed. Monitor renal function and blood counts in at-risk patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Other interactions of Valganciclovir
Frequently asked questions
Can I take Fenoprofen with Valganciclovir?
MediHelp rates the interaction as minor. Fenoprofen and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fenoprofen may slightly raise exposure to ganciclovir, the active metabolite of valganciclovir, by competing for renal secretion. This is mostly relevant with renal impairment because ganciclovir can cause myelosuppression.
How serious is the interaction between Fenoprofen and Valganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor renal function and blood counts in at-risk patients.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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