Drug interactions
Fesoterodine + Methscopolamine
Severity: Moderate
Fesoterodine and Methscopolamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are antimuscarinic drugs, so together they add to peripheral anticholinergic effects, including dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with obstructive conditions are at greater risk.
What this interaction means in plain words
Fesoterodine and Methscopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Avoid duplicate antimuscarinic therapy where possible; if both are required, monitor for urinary retention, constipation and heat intolerance.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fesoterodine
Frequently asked questions
Can I take Fesoterodine with Methscopolamine?
MediHelp rates the interaction as moderate. Fesoterodine and Methscopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinic drugs, so together they add to peripheral anticholinergic effects, including dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older patients and those with obstructive conditions are at greater risk.
How serious is the interaction between Fesoterodine and Methscopolamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid duplicate antimuscarinic therapy where possible; if both are required, monitor for urinary retention, constipation and heat intolerance.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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