Drug interactions
Fesoterodine + Metronidazole
Severity: Minor
Fesoterodine and Metronidazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Metronidazole is not a clinically important CYP3A4 inhibitor, so any rise in fesoterodine active metabolite exposure is expected to be negligible. No meaningful clinical interaction is established.
What this interaction means in plain words
Fesoterodine and Metronidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fesoterodine belongs to Genitourinary; Metronidazole belongs to Anti Parasitic.
Why it happens
Possible weak CYP3A4 inhibition, not well established clinically.
What to do
No action is needed beyond routine monitoring of antimuscarinic adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fesoterodine
Other interactions of Metronidazole
- Ethanol + Metronidazole Contraindicated
- Metronidazole + Pimozide Contraindicated
- Amiodarone + Metronidazole Major
- Disulfiram + Metronidazole Major
- Ergotamine + Metronidazole Major
- Lomitapide + Metronidazole Major
Frequently asked questions
Can I take Fesoterodine with Metronidazole?
MediHelp rates the interaction as minor. Fesoterodine and Metronidazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Metronidazole is not a clinically important CYP3A4 inhibitor, so any rise in fesoterodine active metabolite exposure is expected to be negligible. No meaningful clinical interaction is established.
How serious is the interaction between Fesoterodine and Metronidazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed beyond routine monitoring of antimuscarinic adverse effects.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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