Drug interactions
Fingolimod + Formoterol
Severity: Moderate
Fingolimod and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fingolimod can slow heart rate and prolong the QT interval, and formoterol may add to QT prolongation and cause tachycardia or hypokalemia. This may increase the risk of arrhythmia in susceptible patients.
What this interaction means in plain words
Fingolimod and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Formoterol belongs to Respiratory.
Why it happens
Additive QT prolongation and opposing effects on heart rate, with beta-2 agonist hypokalemia increasing risk.
What to do
Monitor ECG and heart rhythm, especially around fingolimod initiation, and check potassium. Take extra care in patients with existing QT prolongation or bradycardia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Formoterol?
MediHelp rates the interaction as moderate. Fingolimod and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fingolimod can slow heart rate and prolong the QT interval, and formoterol may add to QT prolongation and cause tachycardia or hypokalemia. This may increase the risk of arrhythmia in susceptible patients.
How serious is the interaction between Fingolimod and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and heart rhythm, especially around fingolimod initiation, and check potassium. Take extra care in patients with existing QT prolongation or bradycardia.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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