Drug interactions
Fingolimod + Ixabepilone
Severity: Moderate
Fingolimod and Ixabepilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ixabepilone causes myelosuppression and neutropenia, and fingolimod reduces circulating lymphocytes. Combined use may increase the risk of serious infections.
What this interaction means in plain words
Fingolimod and Ixabepilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic immunosuppression from cytotoxic myelosuppression and fingolimod-induced lymphopenia.
What to do
Monitor blood counts and screen for infection during treatment. Consider interrupting fingolimod while the patient receives myelosuppressive chemotherapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Ixabepilone?
MediHelp rates the interaction as moderate. Fingolimod and Ixabepilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ixabepilone causes myelosuppression and neutropenia, and fingolimod reduces circulating lymphocytes. Combined use may increase the risk of serious infections.
How serious is the interaction between Fingolimod and Ixabepilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and screen for infection during treatment. Consider interrupting fingolimod while the patient receives myelosuppressive chemotherapy.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Pimozide. The full list is on the Fingolimod page.
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