Drug interactions
Fingolimod + Levosalbutamol
Severity: Moderate
Fingolimod and Levosalbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fingolimod causes bradycardia and can prolong the QT interval, whereas beta-2 agonists can cause tachycardia, hypokalemia and QT prolongation at high doses. The combination may increase arrhythmia risk, though this is mainly relevant with high-dose or repeated levosalbutamol.
What this interaction means in plain words
Fingolimod and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Levosalbutamol belongs to Respiratory.
Why it happens
Additive effects on cardiac repolarization and conduction, with beta-agonist hypokalemia increasing susceptibility.
What to do
Monitor ECG and potassium, particularly around fingolimod initiation and with frequent levosalbutamol use. Correct electrolyte abnormalities.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Fingolimod and Levosalbutamol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Levosalbutamol
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Levosalbutamol?
MediHelp rates the interaction as moderate. Fingolimod and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fingolimod causes bradycardia and can prolong the QT interval, whereas beta-2 agonists can cause tachycardia, hypokalemia and QT prolongation at high doses. The combination may increase arrhythmia risk, though this is mainly relevant with high-dose or repeated levosalbutamol.
How serious is the interaction between Fingolimod and Levosalbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium, particularly around fingolimod initiation and with frequent levosalbutamol use. Correct electrolyte abnormalities.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
