Drug interactions
Fingolimod + Thalidomide
Severity: Moderate
Fingolimod and Thalidomide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thalidomide has immunomodulatory effects and can cause neutropenia, and fingolimod reduces circulating lymphocytes. The combination may modestly increase infection risk.
What this interaction means in plain words
Fingolimod and Thalidomide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Thalidomide belongs to Miscellaneous.
Why it happens
Additive immunomodulation and immunosuppression.
What to do
Monitor blood counts and signs of infection. Reassess the need for fingolimod if neutropenia or infection develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Other interactions of Thalidomide
Frequently asked questions
Can I take Fingolimod with Thalidomide?
MediHelp rates the interaction as moderate. Fingolimod and Thalidomide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thalidomide has immunomodulatory effects and can cause neutropenia, and fingolimod reduces circulating lymphocytes. The combination may modestly increase infection risk.
How serious is the interaction between Fingolimod and Thalidomide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and signs of infection. Reassess the need for fingolimod if neutropenia or infection develops.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Pimozide. The full list is on the Fingolimod page.
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