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Drug interactions

Fish oil triglycerides + Naproxen

Severity: Minor

Fish oil triglycerides and Naproxen: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Omega-3 fatty acids have mild antiplatelet effects and may prolong bleeding time when combined with naproxen. Clinically significant bleeding is uncommon but possible.

What this interaction means in plain words

Fish oil triglycerides and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Moderate

Why it happens

Additive modest inhibition of platelet aggregation.

What to do

Monitor for bleeding signs, especially in patients with other bleeding risks. No dose change is usually needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fish oil triglycerides with Naproxen?

MediHelp rates the interaction as minor. Fish oil triglycerides and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omega-3 fatty acids have mild antiplatelet effects and may prolong bleeding time when combined with naproxen. Clinically significant bleeding is uncommon but possible.

How serious is the interaction between Fish oil triglycerides and Naproxen?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding signs, especially in patients with other bleeding risks. No dose change is usually needed.

What other medicines interact with Naproxen?

MediHelp also lists interactions of Naproxen with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Naproxen page.

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