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Drug interactions

Fish oil triglycerides + Paroxetine

Severity: Minor

Fish oil triglycerides and Paroxetine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Omega-3 fatty acids can modestly prolong bleeding time, and SSRIs such as paroxetine impair platelet function. Combined use may add to bleeding tendency, though clinically significant bleeding is uncommon.

What this interaction means in plain words

Fish oil triglycerides and Paroxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Additive antiplatelet effects via reduced platelet aggregation.

What to do

Be aware of the additive bleeding tendency and ask patients to report bruising or bleeding. Monitor more closely if other anticoagulants or antiplatelets are also used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fish oil triglycerides with Paroxetine?

MediHelp rates the interaction as minor. Fish oil triglycerides and Paroxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omega-3 fatty acids can modestly prolong bleeding time, and SSRIs such as paroxetine impair platelet function. Combined use may add to bleeding tendency, though clinically significant bleeding is uncommon.

How serious is the interaction between Fish oil triglycerides and Paroxetine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware of the additive bleeding tendency and ask patients to report bruising or bleeding. Monitor more closely if other anticoagulants or antiplatelets are also used.

What other medicines interact with Paroxetine?

MediHelp also lists interactions of Paroxetine with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Paroxetine page.

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