Drug interactions
Fludrocortisone + Influenza virus vaccine quadrivalent adjuvanted
Severity: Minor
Fludrocortisone and Influenza virus vaccine quadrivalent adjuvanted: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids at supraphysiologic doses can reduce vaccine immune responses. At the usual replacement doses of fludrocortisone, the effect on the response to this inactivated vaccine is expected to be minimal.
What this interaction means in plain words
Fludrocortisone and Influenza virus vaccine quadrivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Immunosuppression from corticosteroids may blunt the antibody response, but only at higher glucocorticoid-equivalent doses.
What to do
Vaccinate as scheduled without stopping fludrocortisone.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fludrocortisone
Frequently asked questions
Can I take Fludrocortisone with Influenza virus vaccine quadrivalent adjuvanted?
MediHelp rates the interaction as minor. Fludrocortisone and Influenza virus vaccine quadrivalent adjuvanted have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids at supraphysiologic doses can reduce vaccine immune responses. At the usual replacement doses of fludrocortisone, the effect on the response to this inactivated vaccine is expected to be minimal.
How serious is the interaction between Fludrocortisone and Influenza virus vaccine quadrivalent adjuvanted?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as scheduled without stopping fludrocortisone.
What other medicines interact with Fludrocortisone?
MediHelp also lists interactions of Fludrocortisone with, for example, Mifepristone, Aldesleukin, Amphotericin b. The full list is on the Fludrocortisone page.
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