Drug interactions
fluoxetine + pimozide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
QT prolongation/arrhythmia risk; contraindicated.
Mechanism of action
CYP inhibition + additive QT.
Clinical management
Contraindicated.
Drug reference
References
Frequently asked questions
Can I take fluoxetine with pimozide?
The interaction is rated: Contraindicated. QT prolongation/arrhythmia risk; contraindicated.
How serious is the interaction between fluoxetine and pimozide?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between fluoxetine and pimozide managed?
Contraindicated.
Why do fluoxetine and pimozide interact?
CYP inhibition + additive QT.
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