Drug interactions
Fluoxymesterone + Insulin glulisine
Severity: Moderate
Fluoxymesterone and Insulin glulisine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgenic steroids such as fluoxymesterone can increase insulin sensitivity and lower blood glucose, which may increase hypoglycemia risk in insulin-treated patients. Insulin dose reduction may be needed.
What this interaction means in plain words
Fluoxymesterone and Insulin glulisine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anabolic androgens alter glucose metabolism and improve insulin sensitivity, adding to insulin effect.
What to do
Monitor blood glucose when starting or stopping fluoxymesterone and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin glulisine
Frequently asked questions
Can I take Fluoxymesterone with Insulin glulisine?
MediHelp rates the interaction as moderate. Fluoxymesterone and Insulin glulisine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Androgenic steroids such as fluoxymesterone can increase insulin sensitivity and lower blood glucose, which may increase hypoglycemia risk in insulin-treated patients. Insulin dose reduction may be needed.
How serious is the interaction between Fluoxymesterone and Insulin glulisine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping fluoxymesterone and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin glulisine?
MediHelp also lists interactions of Insulin glulisine with, for example, Alogliptin-pioglitazone, Ethanol, Pentamidine. The full list is on the Insulin glulisine page.
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