Drug interactions
Fluoxymesterone + Metformin-pioglitazone
Severity: Minor
Fluoxymesterone and Metformin-pioglitazone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens and anabolic steroids may improve or alter insulin sensitivity and glucose levels, and can enhance the effect of antidiabetic drugs. Changes in glycemic control are possible.
What this interaction means in plain words
Fluoxymesterone and Metformin-pioglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Androgen effects on glucose metabolism and insulin sensitivity produce additive pharmacodynamic effects.
What to do
Monitor blood glucose when starting or stopping fluoxymesterone and adjust antidiabetic doses as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-pioglitazone
Frequently asked questions
Can I take Fluoxymesterone with Metformin-pioglitazone?
MediHelp rates the interaction as minor. Fluoxymesterone and Metformin-pioglitazone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens and anabolic steroids may improve or alter insulin sensitivity and glucose levels, and can enhance the effect of antidiabetic drugs. Changes in glycemic control are possible.
How serious is the interaction between Fluoxymesterone and Metformin-pioglitazone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping fluoxymesterone and adjust antidiabetic doses as needed.
What other medicines interact with Metformin-pioglitazone?
MediHelp also lists interactions of Metformin-pioglitazone with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Metformin-pioglitazone page.
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