Drug reference

metformin-pioglitazone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Insulin sensitizers)

Mechanism of action

Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Pioglitazone: Thiazolidinedione; insulin-sensitizing agent that acts by enhancing peripheral glucose utilization

Common side effects

  • Dizziness
  • Nausea
  • Lower limb edema
  • Weight gain
  • Diarrhea

Related conditions

Frequently asked questions

What drug class is metformin-pioglitazone?

metformin-pioglitazone belongs to: Endocrine.

How does metformin-pioglitazone work?

Metformin: Biguanide; acts by decreasing endogenous hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Pioglitazone: Thiazolidinedione; insulin-sensitizing agent that acts by enhancing peripheral glucose utilization

What are the common side effects of metformin-pioglitazone?

Dizziness, Nausea, Lower limb edema, Weight gain, Diarrhea

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