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Drug interactions

Flurbiprofen + Ginkgo biloba

Severity: Moderate

Flurbiprofen and Ginkgo biloba: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ginkgo contains ginkgolides that antagonize platelet-activating factor, and bleeding has been reported with ginkgo and antiplatelet drugs. Combined with flurbiprofen, bleeding risk may increase.

What this interaction means in plain words

Flurbiprofen and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive antiplatelet effects: PAF antagonism by ginkgo and COX inhibition by flurbiprofen.

What to do

Advise avoiding ginkgo with regular NSAID use, or monitor for bruising and bleeding.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Flurbiprofen with Ginkgo biloba?

MediHelp rates the interaction as moderate. Flurbiprofen and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo contains ginkgolides that antagonize platelet-activating factor, and bleeding has been reported with ginkgo and antiplatelet drugs. Combined with flurbiprofen, bleeding risk may increase.

How serious is the interaction between Flurbiprofen and Ginkgo biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding ginkgo with regular NSAID use, or monitor for bruising and bleeding.

What other medicines interact with Flurbiprofen?

MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.

Full monographs, dosing and an interaction checker in the MediHelp app

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