Drug interactions
Flurbiprofen + Noni juice
Severity: Moderate
Flurbiprofen and Noni juice: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Noni juice is high in potassium, and NSAIDs can impair renal potassium excretion. Together they may raise serum potassium, particularly in patients with kidney disease or on other potassium-raising drugs.
What this interaction means in plain words
Flurbiprofen and Noni juice can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Dietary potassium load combined with NSAID-induced reduction in renal prostaglandin-mediated potassium excretion.
What to do
Monitor serum potassium in patients with renal impairment or taking ACE inhibitors, ARBs or potassium-sparing diuretics, and limit noni juice intake.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Frequently asked questions
Can I take Flurbiprofen with Noni juice?
MediHelp rates the interaction as moderate. Flurbiprofen and Noni juice can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Noni juice is high in potassium, and NSAIDs can impair renal potassium excretion. Together they may raise serum potassium, particularly in patients with kidney disease or on other potassium-raising drugs.
How serious is the interaction between Flurbiprofen and Noni juice?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with renal impairment or taking ACE inhibitors, ARBs or potassium-sparing diuretics, and limit noni juice intake.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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