Drug interactions
Flurbiprofen + Ticarcillin
Severity: Moderate
Flurbiprofen and Ticarcillin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ticarcillin can impair platelet function at high doses, and flurbiprofen also inhibits platelets, so bleeding risk may be increased. Competition for renal tubular secretion may modestly raise levels of either drug.
What this interaction means in plain words
Flurbiprofen and Ticarcillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive platelet dysfunction and possible competition for renal tubular secretion.
What to do
Monitor for bleeding and for renal function changes, particularly with high-dose ticarcillin or renal impairment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Frequently asked questions
Can I take Flurbiprofen with Ticarcillin?
MediHelp rates the interaction as moderate. Flurbiprofen and Ticarcillin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ticarcillin can impair platelet function at high doses, and flurbiprofen also inhibits platelets, so bleeding risk may be increased. Competition for renal tubular secretion may modestly raise levels of either drug.
How serious is the interaction between Flurbiprofen and Ticarcillin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and for renal function changes, particularly with high-dose ticarcillin or renal impairment.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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