Skip to content

Drug interactions

Fluticasone-salmeterol + Pholcodine

Severity: Minor

Fluticasone-salmeterol and Pholcodine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Pholcodine is an opioid cough suppressant that may cause drowsiness. No relevant pharmacologic interaction with salmeterol is established.

What this interaction means in plain words

Fluticasone-salmeterol and Pholcodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

No established mechanism; effects are independent.

What to do

No specific action is needed; counsel about drowsiness from pholcodine.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Fluticasone-salmeterol and Pholcodine, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Fluticasone-salmeterol with Pholcodine?

MediHelp rates the interaction as minor. Fluticasone-salmeterol and Pholcodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pholcodine is an opioid cough suppressant that may cause drowsiness. No relevant pharmacologic interaction with salmeterol is established.

How serious is the interaction between Fluticasone-salmeterol and Pholcodine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; counsel about drowsiness from pholcodine.

What other medicines interact with Fluticasone-salmeterol?

MediHelp also lists interactions of Fluticasone-salmeterol with, for example, Darunavir, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Fosamprenavir. The full list is on the Fluticasone-salmeterol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in