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Drug interactions

Fluticasone-salmeterol + Quazepam

Severity: Minor

Fluticasone-salmeterol and Quazepam: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Quazepam is a benzodiazepine hypnotic causing sedation and respiratory depression. Salmeterol does not meaningfully offset this, so the concern is benzodiazepine use in patients with respiratory disease.

What this interaction means in plain words

Fluticasone-salmeterol and Quazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

No established pharmacologic interaction; effects are independent.

What to do

Use the lowest effective quazepam dose and monitor respiratory status in patients with severe COPD.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fluticasone-salmeterol with Quazepam?

MediHelp rates the interaction as minor. Fluticasone-salmeterol and Quazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quazepam is a benzodiazepine hypnotic causing sedation and respiratory depression. Salmeterol does not meaningfully offset this, so the concern is benzodiazepine use in patients with respiratory disease.

How serious is the interaction between Fluticasone-salmeterol and Quazepam?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective quazepam dose and monitor respiratory status in patients with severe COPD.

What other medicines interact with Fluticasone-salmeterol?

MediHelp also lists interactions of Fluticasone-salmeterol with, for example, Darunavir, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Fosamprenavir. The full list is on the Fluticasone-salmeterol page.

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