Drug interactions
Fluvastatin + Miconazole vaginal
Severity: Minor
Fluvastatin and Miconazole vaginal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Miconazole inhibits CYP2C9 and vaginal use can produce some systemic absorption, which could modestly raise fluvastatin levels. The effect is generally small and clinical reports are limited.
What this interaction means in plain words
Fluvastatin and Miconazole vaginal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Systemically absorbed miconazole inhibits CYP2C9 metabolism of fluvastatin.
What to do
Counsel on muscle symptoms during prolonged or repeated miconazole courses; no routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluvastatin
- Cyclosporin + Fluvastatin Major
- Fluvastatin + Gemfibrozil Major
- Fluvastatin + Letermovir Major
- Fluvastatin + Red yeast rice Major
- Apalutamide + Fluvastatin Moderate
- Cholestyramine + Fluvastatin Moderate
Frequently asked questions
Can I take Fluvastatin with Miconazole vaginal?
MediHelp rates the interaction as minor. Fluvastatin and Miconazole vaginal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Miconazole inhibits CYP2C9 and vaginal use can produce some systemic absorption, which could modestly raise fluvastatin levels. The effect is generally small and clinical reports are limited.
How serious is the interaction between Fluvastatin and Miconazole vaginal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on muscle symptoms during prolonged or repeated miconazole courses; no routine dose change is needed.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporin, Gemfibrozil, Letermovir. The full list is on the Fluvastatin page.
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