Drug interactions
Formoterol + Paroxetine
Severity: Minor
Formoterol and Paroxetine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Paroxetine has a low potential for QT prolongation compared with other antidepressants, and formoterol adds only modest QTc and potassium effects. The combined clinical risk is small but may matter in patients with other arrhythmia risk factors.
What this interaction means in plain words
Formoterol and Paroxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Formoterol belongs to Respiratory; Paroxetine belongs to Central Nervous System.
Why it happens
Possible small additive effects on QT interval and beta2-agonist-induced hypokalemia.
What to do
No routine action is needed; check ECG and electrolytes only in patients with other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Paroxetine
- Isocarboxazid + Paroxetine Contraindicated
- Methylene blue + Paroxetine Contraindicated
- Paroxetine + Phenelzine Contraindicated
- Paroxetine + Pimozide Contraindicated
- Paroxetine + Procarbazine Contraindicated
- Paroxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Formoterol with Paroxetine?
MediHelp rates the interaction as minor. Formoterol and Paroxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Paroxetine has a low potential for QT prolongation compared with other antidepressants, and formoterol adds only modest QTc and potassium effects. The combined clinical risk is small but may matter in patients with other arrhythmia risk factors.
How serious is the interaction between Formoterol and Paroxetine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; check ECG and electrolytes only in patients with other QT risk factors.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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