Drug interactions
Formoterol + Pasireotide
Severity: Moderate
Formoterol and Pasireotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can prolong the QT interval, so using them together may add to the risk of ventricular arrhythmias including torsades de pointes. Pasireotide also causes bradycardia, which increases susceptibility, and the risk is greater if potassium or magnesium is low.
What this interaction means in plain words
Formoterol and Pasireotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Pasireotide belongs to Endocrine.
Why it happens
Additive pharmacodynamic QT prolongation, with beta-agonist-induced hypokalemia as a further contributor.
What to do
Obtain a baseline ECG and correct potassium and magnesium before and during combined use. Repeat ECG monitoring if symptoms, bradycardia or other QT-prolonging drugs are present.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Pasireotide
- Dronedarone + Pasireotide Contraindicated
- Pasireotide + Pimozide Contraindicated
- Amiodarone + Pasireotide Major
- Amisulpride + Pasireotide Major
- Amitriptyline + Pasireotide Major
- Anagrelide + Pasireotide Major
Frequently asked questions
Can I take Formoterol with Pasireotide?
MediHelp rates the interaction as moderate. Formoterol and Pasireotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QT interval, so using them together may add to the risk of ventricular arrhythmias including torsades de pointes. Pasireotide also causes bradycardia, which increases susceptibility, and the risk is greater if potassium or magnesium is low.
How serious is the interaction between Formoterol and Pasireotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct potassium and magnesium before and during combined use. Repeat ECG monitoring if symptoms, bradycardia or other QT-prolonging drugs are present.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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