Drug interactions
Formoterol + Pitolisant
Severity: Moderate
Formoterol and Pitolisant: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pitolisant can prolong the QT interval modestly, and formoterol may contribute through QT effects and hypokalemia. The combination may raise arrhythmia risk, particularly with other risk factors.
What this interaction means in plain words
Formoterol and Pitolisant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Pitolisant belongs to Central Nervous System.
Why it happens
Additive QT prolongation (pharmacodynamic).
What to do
Avoid in patients with known QT prolongation or other risk factors. Otherwise consider a baseline ECG and monitor potassium.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Pitolisant
- Alfuzosin + Pitolisant Major
- Amiodarone + Pitolisant Major
- Amisulpride + Pitolisant Major
- Anagrelide + Pitolisant Major
- Asenapine + Pitolisant Major
- Bupropion + Pitolisant Major
Frequently asked questions
Can I take Formoterol with Pitolisant?
MediHelp rates the interaction as moderate. Formoterol and Pitolisant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pitolisant can prolong the QT interval modestly, and formoterol may contribute through QT effects and hypokalemia. The combination may raise arrhythmia risk, particularly with other risk factors.
How serious is the interaction between Formoterol and Pitolisant?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with known QT prolongation or other risk factors. Otherwise consider a baseline ECG and monitor potassium.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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