Drug interactions
Formoterol + Triamterene
Severity: Minor
Formoterol and Triamterene: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Formoterol can lower serum potassium through cellular uptake, while triamterene is potassium-sparing and tends to raise it. The effects largely offset each other, so a significant change is uncommon, though potassium may shift in renal impairment.
What this interaction means in plain words
Formoterol and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Formoterol belongs to Respiratory; Triamterene belongs to Cardiovascular.
Why it happens
Opposing effects on serum potassium: beta2-mediated cellular uptake versus reduced renal potassium excretion.
What to do
No routine action is needed; monitor potassium in patients with renal impairment or on high-dose beta-agonist therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Triamterene
- Amiloride + Triamterene Contraindicated
- Eplerenone + Triamterene Contraindicated
- Potassium citrate / citric acid + Triamterene Contraindicated
- Potassium citrate + Triamterene Contraindicated
- Spironolactone + Triamterene Contraindicated
- Aceclofenac + Triamterene Major
Frequently asked questions
Can I take Formoterol with Triamterene?
MediHelp rates the interaction as minor. Formoterol and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Formoterol can lower serum potassium through cellular uptake, while triamterene is potassium-sparing and tends to raise it. The effects largely offset each other, so a significant change is uncommon, though potassium may shift in renal impairment.
How serious is the interaction between Formoterol and Triamterene?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor potassium in patients with renal impairment or on high-dose beta-agonist therapy.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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