Drug reference
triamterene
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Diuretics)
Mechanism of action
Direct effect on renal distal tubule to inhibit Na+ reabsorption, Inhibits Na/K-ATPase, decreases Ca++ , Mg++ and hydrogen excretion
Common side effects
- Dizziness
- Edema
- Fatigue
- CHF
- Hypotension
- Photosensitivity
Contraindications
- Hypersensitivity to triamterene Anuria, severe liver disease, renal failure Hyperkalemia Concomitant use with K+-sparing diuretic, or K supplementation
Known interactions (4)
- amiloride + triamterene Contraindicated
- eplerenone + triamterene Contraindicated
- drospirenone + triamterene Moderate
- ethinyl estradiol-drospirenone + triamterene Moderate
Related conditions
Frequently asked questions
What drug class is triamterene?
triamterene belongs to: Cardiovascular.
How does triamterene work?
Direct effect on renal distal tubule to inhibit Na+ reabsorption, Inhibits Na/K-ATPase, decreases Ca++ , Mg++ and hydrogen excretion
What are the common side effects of triamterene?
Dizziness, Edema, Fatigue, CHF, Hypotension, Photosensitivity
Which drugs interact with triamterene?
amiloride, eplerenone, drospirenone, ethinyl estradiol-drospirenone
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