Drug interactions
Forskolin + Ibuprofen
Severity: Moderate
Forskolin and Ibuprofen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin is a herbal product reported to have antiplatelet activity in laboratory studies. Taken with ibuprofen, it could theoretically add to bleeding risk, but clinical data are lacking.
What this interaction means in plain words
Forskolin and Ibuprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive platelet inhibition; forskolin raises cAMP in platelets, which inhibits aggregation, while ibuprofen inhibits cyclooxygenase.
What to do
Ask patients about supplement use and advise avoiding forskolin during regular NSAID therapy. Monitor for bruising or bleeding if the combination continues.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ibuprofen
- Ibuprofen + Ketorolac Contraindicated
- Ibuprofen + Ketorolac intranasal Contraindicated
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
- Apixaban + Ibuprofen Major
Frequently asked questions
Can I take Forskolin with Ibuprofen?
MediHelp rates the interaction as moderate. Forskolin and Ibuprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Forskolin is a herbal product reported to have antiplatelet activity in laboratory studies. Taken with ibuprofen, it could theoretically add to bleeding risk, but clinical data are lacking.
How serious is the interaction between Forskolin and Ibuprofen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about supplement use and advise avoiding forskolin during regular NSAID therapy. Monitor for bruising or bleeding if the combination continues.
What other medicines interact with Ibuprofen?
MediHelp also lists interactions of Ibuprofen with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Ibuprofen page.
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