Drug interactions
Forskolin + Meclofenamic acid
Severity: Moderate
Forskolin and Meclofenamic acid: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin raises intracellular cAMP and can inhibit platelet aggregation, so it may add to the antiplatelet effect of meclofenamic acid. This could increase bruising or bleeding, although clinical data are scarce.
What this interaction means in plain words
Forskolin and Meclofenamic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Theoretical additive antiplatelet effect: adenylate cyclase activation by forskolin plus NSAID COX-1 inhibition.
What to do
Avoid unsupervised forskolin supplements with NSAIDs. If used together, monitor for bleeding signs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Meclofenamic acid
- Ketorolac intranasal + Meclofenamic acid Contraindicated
- Ketorolac + Meclofenamic acid Contraindicated
- Aceclofenac + Meclofenamic acid Major
- Acemetacin + Meclofenamic acid Major
- Alteplase + Meclofenamic acid Major
- Amiloride + Meclofenamic acid Major
Frequently asked questions
Can I take Forskolin with Meclofenamic acid?
MediHelp rates the interaction as moderate. Forskolin and Meclofenamic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Forskolin raises intracellular cAMP and can inhibit platelet aggregation, so it may add to the antiplatelet effect of meclofenamic acid. This could increase bruising or bleeding, although clinical data are scarce.
How serious is the interaction between Forskolin and Meclofenamic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unsupervised forskolin supplements with NSAIDs. If used together, monitor for bleeding signs.
What other medicines interact with Meclofenamic acid?
MediHelp also lists interactions of Meclofenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meclofenamic acid page.
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