Drug interactions
Forskolin + Naproxen
Severity: Minor
Forskolin and Naproxen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin raises cyclic AMP and inhibits platelet aggregation in vitro, so it could add to naproxen's antiplatelet effect. Clinical evidence is lacking.
What this interaction means in plain words
Forskolin and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive antiplatelet effect via adenylate cyclase activation.
What to do
Counsel patients to report bruising or bleeding if supplement use is continued.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Naproxen
- Ketorolac intranasal + Naproxen Contraindicated
- Ketorolac + Naproxen Contraindicated
- Aceclofenac + Naproxen Major
- Acemetacin + Naproxen Major
- Acetylsalicylic acid + Naproxen Major
- Alteplase + Naproxen Major
Frequently asked questions
Can I take Forskolin with Naproxen?
MediHelp rates the interaction as minor. Forskolin and Naproxen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin raises cyclic AMP and inhibits platelet aggregation in vitro, so it could add to naproxen's antiplatelet effect. Clinical evidence is lacking.
How serious is the interaction between Forskolin and Naproxen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report bruising or bleeding if supplement use is continued.
What other medicines interact with Naproxen?
MediHelp also lists interactions of Naproxen with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Naproxen page.
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