Drug interactions
Forskolin + Tolmetin
Severity: Minor
Forskolin and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin raises intracellular cAMP and inhibits platelet aggregation in vitro. It could add to the antiplatelet effect of tolmetin, though clinical data are lacking.
What this interaction means in plain words
Forskolin and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive platelet inhibition via cAMP elevation and COX inhibition.
What to do
Counsel patients to report bruising or bleeding. No routine monitoring is required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Forskolin with Tolmetin?
MediHelp rates the interaction as minor. Forskolin and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin raises intracellular cAMP and inhibits platelet aggregation in vitro. It could add to the antiplatelet effect of tolmetin, though clinical data are lacking.
How serious is the interaction between Forskolin and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report bruising or bleeding. No routine monitoring is required.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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