Drug interactions
Fosamprenavir + Raltegravir
Severity: Minor
Fosamprenavir and Raltegravir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fosamprenavir may reduce raltegravir concentrations. The reduction is generally not considered clinically significant.
What this interaction means in plain words
Fosamprenavir and Raltegravir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Mechanism not firmly established; possible induction of UGT1A1-mediated glucuronidation.
What to do
No dose adjustment is usually needed; monitor virologic response.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Raltegravir
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Raltegravir Contraindicated
- Aluminum hydroxide / magnesium carbonate + Raltegravir Major
- Aluminum hydroxide / magnesium trisilicate + Raltegravir Major
- Aluminum hydroxide + Raltegravir Major
- Atidarsagene autotemcel + Raltegravir Major
- Betibeglogene autotemcel + Raltegravir Major
Frequently asked questions
Can I take Fosamprenavir with Raltegravir?
MediHelp rates the interaction as minor. Fosamprenavir and Raltegravir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fosamprenavir may reduce raltegravir concentrations. The reduction is generally not considered clinically significant.
How serious is the interaction between Fosamprenavir and Raltegravir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed; monitor virologic response.
What other medicines interact with Raltegravir?
MediHelp also lists interactions of Raltegravir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Raltegravir page.
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