Drug interactions
Foscarnet + Olanzapine
Severity: Moderate
Foscarnet and Olanzapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olanzapine has a modest QT-prolonging effect and foscarnet may add to this while also causing electrolyte depletion. The combination may increase arrhythmia risk in susceptible patients.
What this interaction means in plain words
Foscarnet and Olanzapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Olanzapine belongs to Central Nervous System.
Why it happens
Additive QT prolongation with foscarnet-related electrolyte abnormalities.
What to do
Obtain a baseline ECG, monitor electrolytes and ECG during foscarnet infusion, and correct deficits promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Olanzapine
Frequently asked questions
Can I take Foscarnet with Olanzapine?
MediHelp rates the interaction as moderate. Foscarnet and Olanzapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Olanzapine has a modest QT-prolonging effect and foscarnet may add to this while also causing electrolyte depletion. The combination may increase arrhythmia risk in susceptible patients.
How serious is the interaction between Foscarnet and Olanzapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG, monitor electrolytes and ECG during foscarnet infusion, and correct deficits promptly.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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