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Drug interactions

Foscarnet + Olodaterol inhaled

Severity: Moderate

Foscarnet and Olodaterol inhaled: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Foscarnet can prolong the QT interval and disturb electrolytes, while olodaterol as a beta2 agonist may cause tachycardia and hypokalemia. The combination may increase the risk of ventricular arrhythmias, although systemic exposure to inhaled olodaterol is low.

What this interaction means in plain words

Foscarnet and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive QT prolongation and beta2-agonist-related hypokalemia and cardiac stimulation.

What to do

Monitor ECG and serum potassium, magnesium and calcium during foscarnet therapy. Correct electrolyte disturbances and use olodaterol at the labeled dose only.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Foscarnet with Olodaterol inhaled?

MediHelp rates the interaction as moderate. Foscarnet and Olodaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Foscarnet can prolong the QT interval and disturb electrolytes, while olodaterol as a beta2 agonist may cause tachycardia and hypokalemia. The combination may increase the risk of ventricular arrhythmias, although systemic exposure to inhaled olodaterol is low.

How serious is the interaction between Foscarnet and Olodaterol inhaled?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium, magnesium and calcium during foscarnet therapy. Correct electrolyte disturbances and use olodaterol at the labeled dose only.

What other medicines interact with Foscarnet?

MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.

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