Drug interactions
Foscarnet + Sodium sulfate / potassium sulfate / magnesium sulfate
Severity: Moderate
Foscarnet and Sodium sulfate / potassium sulfate / magnesium sulfate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Foscarnet commonly causes hypocalcemia, hypomagnesemia and other electrolyte disturbances that can lead to seizures and arrhythmias. Sulfate-based bowel preparations cause fluid and electrolyte shifts, which may add to these effects and to renal risk.
What this interaction means in plain words
Foscarnet and Sodium sulfate / potassium sulfate / magnesium sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive fluid and electrolyte disturbances, with volume depletion increasing foscarnet nephrotoxicity.
What to do
Ensure adequate hydration and check calcium, magnesium, potassium and creatinine before and after the bowel preparation. Correct abnormalities before continuing foscarnet.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Foscarnet with Sodium sulfate / potassium sulfate / magnesium sulfate?
MediHelp rates the interaction as moderate. Foscarnet and Sodium sulfate / potassium sulfate / magnesium sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Foscarnet commonly causes hypocalcemia, hypomagnesemia and other electrolyte disturbances that can lead to seizures and arrhythmias. Sulfate-based bowel preparations cause fluid and electrolyte shifts, which may add to these effects and to renal risk.
How serious is the interaction between Foscarnet and Sodium sulfate / potassium sulfate / magnesium sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate hydration and check calcium, magnesium, potassium and creatinine before and after the bowel preparation. Correct abnormalities before continuing foscarnet.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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