Drug interactions
Foscarnet + Venlafaxine
Severity: Moderate
Foscarnet and Venlafaxine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Venlafaxine can prolong QT, particularly in overdose, and foscarnet may add to this while causing electrolyte disturbances. The combination may increase the risk of arrhythmia.
What this interaction means in plain words
Foscarnet and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Venlafaxine belongs to Central Nervous System.
Why it happens
Additive QT prolongation with electrolyte disturbance.
What to do
Monitor ECG and electrolytes, especially in patients with cardiac disease. Correct deficits and consider alternatives if QTc becomes prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Venlafaxine
- Isocarboxazid + Venlafaxine Contraindicated
- Methylene blue + Venlafaxine Contraindicated
- Phenelzine + Venlafaxine Contraindicated
- Procarbazine + Venlafaxine Contraindicated
- Rasagiline + Venlafaxine Contraindicated
- Safinamide + Venlafaxine Contraindicated
Frequently asked questions
Can I take Foscarnet with Venlafaxine?
MediHelp rates the interaction as moderate. Foscarnet and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Venlafaxine can prolong QT, particularly in overdose, and foscarnet may add to this while causing electrolyte disturbances. The combination may increase the risk of arrhythmia.
How serious is the interaction between Foscarnet and Venlafaxine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes, especially in patients with cardiac disease. Correct deficits and consider alternatives if QTc becomes prolonged.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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