Drug interactions
Fosinopril + Synthetic human angiotensin ii
Severity: Moderate
Fosinopril and Synthetic human angiotensin ii: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors reduce endogenous angiotensin II generation, which makes patients more sensitive to the pressor effect of infused angiotensin II. Blood pressure response may therefore be greater than anticipated.
What this interaction means in plain words
Fosinopril and Synthetic human angiotensin ii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
ACE inhibition lowers baseline angiotensin II, increasing sensitivity to exogenous angiotensin II.
What to do
Start angiotensin II at the lowest dose and titrate to blood pressure. Monitor blood pressure continuously during infusion.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Fosinopril and Synthetic human angiotensin ii, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Fosinopril
- Aliskiren + Fosinopril Contraindicated
- Fosinopril + Protein a column Contraindicated
- Fosinopril + Sacubitril / valsartan Contraindicated
- Fosinopril + Sacubitril-valsartan Contraindicated
- Amifostine + Fosinopril Major
- Amiloride + Fosinopril Major
Frequently asked questions
Can I take Fosinopril with Synthetic human angiotensin ii?
MediHelp rates the interaction as moderate. Fosinopril and Synthetic human angiotensin ii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. ACE inhibitors reduce endogenous angiotensin II generation, which makes patients more sensitive to the pressor effect of infused angiotensin II. Blood pressure response may therefore be greater than anticipated.
How serious is the interaction between Fosinopril and Synthetic human angiotensin ii?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start angiotensin II at the lowest dose and titrate to blood pressure. Monitor blood pressure continuously during infusion.
What other medicines interact with Fosinopril?
MediHelp also lists interactions of Fosinopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Fosinopril page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
