Drug interactions
Frovatriptan + Lsd
Severity: Moderate
Frovatriptan and Lsd: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
LSD is a potent serotonin receptor agonist, and frovatriptan also stimulates serotonin receptors. Together they may add to serotonergic effects, and LSD itself is an illicit drug with unpredictable effects.
What this interaction means in plain words
Frovatriptan and Lsd can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive serotonin receptor agonism.
What to do
Counsel patients to avoid LSD. Monitor for serotonin syndrome and hypertension if exposure occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Frovatriptan
- Almotriptan + Frovatriptan Contraindicated
- Dihydroergotamine intranasal + Frovatriptan Contraindicated
- Dihydroergotamine + Frovatriptan Contraindicated
- Eletriptan + Frovatriptan Contraindicated
- Ergoloid mesylates + Frovatriptan Contraindicated
- Ergotamine + Frovatriptan Contraindicated
Frequently asked questions
Can I take Frovatriptan with Lsd?
MediHelp rates the interaction as moderate. Frovatriptan and Lsd can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. LSD is a potent serotonin receptor agonist, and frovatriptan also stimulates serotonin receptors. Together they may add to serotonergic effects, and LSD itself is an illicit drug with unpredictable effects.
How serious is the interaction between Frovatriptan and Lsd?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid LSD. Monitor for serotonin syndrome and hypertension if exposure occurs.
What other medicines interact with Frovatriptan?
MediHelp also lists interactions of Frovatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Frovatriptan page.
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