Drug interactions
Frovatriptan + Tobacco use
Severity: Minor
Frovatriptan and Tobacco use: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tobacco smoking induces CYP1A2 and may slightly reduce frovatriptan levels. The clinical effect is expected to be minimal.
What this interaction means in plain words
Frovatriptan and Tobacco use have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Smoke-related induction of CYP1A2 increases frovatriptan clearance.
What to do
No dose change is required. Reassess triptan effectiveness if tobacco use starts or stops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Frovatriptan
- Almotriptan + Frovatriptan Contraindicated
- Dihydroergotamine intranasal + Frovatriptan Contraindicated
- Dihydroergotamine + Frovatriptan Contraindicated
- Eletriptan + Frovatriptan Contraindicated
- Ergoloid mesylates + Frovatriptan Contraindicated
- Ergotamine + Frovatriptan Contraindicated
Frequently asked questions
Can I take Frovatriptan with Tobacco use?
MediHelp rates the interaction as minor. Frovatriptan and Tobacco use have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tobacco smoking induces CYP1A2 and may slightly reduce frovatriptan levels. The clinical effect is expected to be minimal.
How serious is the interaction between Frovatriptan and Tobacco use?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is required. Reassess triptan effectiveness if tobacco use starts or stops.
What other medicines interact with Frovatriptan?
MediHelp also lists interactions of Frovatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Frovatriptan page.
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