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Drug interactions

Galantamine + Quinupristin / dalfopristin

Severity: Minor

Galantamine and Quinupristin / dalfopristin: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Quinupristin/dalfopristin inhibits CYP3A4 and may increase galantamine concentrations. It is given only short term by infusion, so the effect is limited, but cholinergic adverse effects may be heightened.

What this interaction means in plain words

Galantamine and Quinupristin / dalfopristin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Inhibition of CYP3A4-mediated galantamine metabolism.

What to do

No dose change is needed; monitor heart rate and gastrointestinal tolerance during the antibiotic course.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Galantamine with Quinupristin / dalfopristin?

MediHelp rates the interaction as minor. Galantamine and Quinupristin / dalfopristin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quinupristin/dalfopristin inhibits CYP3A4 and may increase galantamine concentrations. It is given only short term by infusion, so the effect is limited, but cholinergic adverse effects may be heightened.

How serious is the interaction between Galantamine and Quinupristin / dalfopristin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor heart rate and gastrointestinal tolerance during the antibiotic course.

What other medicines interact with Galantamine?

MediHelp also lists interactions of Galantamine with, for example, Memantine-donepezil, Physostigmine, Ponesimod. The full list is on the Galantamine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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